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Warfarin is a coumarin anticoagulant, which has anti-vitamin K effect in vivo. It can inhibit the synthesis of coagulation factors II, VII, IX and VII in the liver which are participated by vitamin K. There was no resistance to coagulation factors II, _, _and_in blood. Therefore, it can not be used as an in vitro anticoagulant. In vivo anticoagulant also needs active coagulation factor consumption before it can be effective, and its effect and maintenance time are longer. It is mainly used to prevent and treat thromboembolic diseases.
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